Comprehensive Genomic Studies
نویسندگان
چکیده
منابع مشابه
Comprehensive genomic studies: emerging regulatory, strategic, and quality assurance challenges for biorepositories.
As part of the molecular revolution sweeping medicine, comprehensive genomic studies are adding powerful dimensions to medical research. However, their power exposes new regulatory, strategic, and quality assurance challenges for biorepositories. A key issue is that unlike other research techniques commonly applied to banked specimens, nucleic acid sequencing, if sufficiently extensive, yields ...
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A dense set of single nucleotide polymorphisms (SNP) covering the genome and an efficient method to assess SNP genotypes are expected to be available in the near future. An outstanding question is how to use these technologies efficiently to identify genes affecting liability to complex disorders. To achieve this goal, we propose a statistical method that has several optimal properties: It can ...
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Description MEFV is the gene responsible for familial Mediterranean fever, an autosomal recessive condition mostly seen in Jews, Armenians, Arabs, and Turks, characterized by recurrent episodes of painful inflammation in the abdomen, chest, and/or joints. The gene expresses itself mostly in peripheral blood leucocytes, particularly in mature granulocytes and their precursors. The expressed prot...
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ژورنال
عنوان ژورنال: American Journal of Clinical Pathology
سال: 2012
ISSN: 0002-9173,1943-7722
DOI: 10.1309/ajcpxba69lnscvmh